首页 工具
登录
购物车

搜索结果

Search Results for " insulin receptor "
Targets Recommended: IGF-1R

127

抑制剂 & 化合物

13

天然产物

34

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求,可以联系我们专业顾问为您提供针对性的合理建议。     QQ咨询       网站留言咨询

提交您的定制咨询

点击图片重新获取验证码
Cat. No. Product Name Target Signaling Pathways
T8221 Insulin (human)

INSULIN,甘精胰岛素,胰岛素,Insulin(human)

IGF-1R Tyrosine Kinase/Adaptors
Insulin (human) 是一种多肽激素,可以促进糖原的合成,调节血液中的葡萄糖水平。Insulin (human) 具有降血糖活性,临床上用于治疗糖尿病患者的高血糖。
TP1125 Insulin(cattle)

牛胰岛素,Insulin from bovine pancreas,胰岛素

IGF-1R Tyrosine Kinase/Adaptors
Insulin cattle (Insulin from bovine pancreas) 是一种在胰腺 β 细胞中产生的两链多肽激素,在很多哺乳动物细胞培养体系中用作生长因子。
TP1259 [pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153)

[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor 1142-1153,Insulin Receptor 1142-1153

[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153) functions as a substrate for insulin receptor tyrosine kinase. This substance effectively binds to insulin and exhibits the potential for utilization in scientific research and medical applications.
T8773 MID-1

Others; IGF-1R Others; Tyrosine Kinase/Adaptors
MID-1 是 MG53-IRS-1 相互作用的抑制剂,能够破坏 MG53 与 IRS-1 的分子缔合,并消除 MG53 诱导的 IRS-1 泛素化和骨骼肌降解,升高 IRS-1 表达水平,增加胰岛素信号传导和葡萄糖摄取。
T8348 Phentolamine

Adrenergic Receptor GPCR/G Protein; Neuroscience
Phentolamine 是一种 alpha-1 和 alpha-2 选择性肾上腺素能受体拮抗剂。
T9030 SU4984

FGFR; IGF-1R; PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
SU4984 是蛋白质酪氨酸激酶抑制剂,能够抑制成纤维细胞生长因子受体 1 (FGFR1) (IC50:10-20 μM),还能够抑制血小板衍生的生长因子受体和胰岛素受体的活性。它可用于研究癌症。
T6003 GSK1904529A

GSK 4529

Apoptosis; Raf; VEGFR; IGF-1R; Syk Angiogenesis; Apoptosis; MAPK; Tyrosine Kinase/Adaptors
GSK1904529A (GSK 4529) 是一种选择性,具有口服活性和 ATP 竞争性的胰岛素样生长因子 1 受体和胰岛素受体抑制剂,IC50值分别为 27 和 25 nM。它具有抗肿瘤活性。
T21761 HNMPA

IGF-1R Tyrosine Kinase/Adaptors
HNMPA 是膜不可渗透的胰岛素受体酪氨酸激酶 (insulin receptor tyrosine kinase) 抑制剂。HNMPA 可以抑制人胰岛素受体的酪氨酸和丝氨酸自磷酸化。HNMPA 对环 AMP 依赖性蛋白激酶或蛋白激酶 C 活性没有影响。
T2349 BMS-754807

Trk receptor; c-Met/HGFR; IGF-1R Tyrosine Kinase/Adaptors
BMS754807 是一种可逆的IGF-1R 抑制剂 (IC50:1.8 nM,Ki<2 nM),也是一种可逆的IR 抑制剂 (IC50:7 nM,Ki<2 nM)。它也抑制 Met (IC50:6 nM),RON (IC50:44 nM),TrkA (IC50:7 nM),TrkB (IC50:4 nM),AurA (IC50:9 nM) 和 AurB (IC50:25 nM) 的活性。
T3079 GSK1838705A

IGF-1R; JNK; S6 Kinase; ALK Angiogenesis; MAPK; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
GSK1838705A 是一种高效的、可逆的IGF-IR (IC50:2.0 nM) 和胰岛素受体 (IC50:1.6 nM)抑制剂,也可抑制ALK (IC50:0.5 nM)。
T10539 BIBO3304 TFA

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
BIBO3304 TFA 是一种可口服的、选择性的神经肽 Y(NPY) Y1受体高效拮抗剂,对人和大鼠 Y1 受体均具有高亲和力,IC50分别为 0.38 和 0.72 nM。
T9609 GRK5-IN-2

GRK GPCR/G Protein
GRK5-IN-2 是基于吡啶的双环化合物,抑制 G 蛋白偶联受体激酶 5 。它调节胰岛素的表达和/或释放,在代谢疾病中有研究价值。
TQ0020 AMG 837 calcium hydrate

GPR Endocrinology/Hormones; GPCR/G Protein
AMG 837 calcium hydrate 是口服有效的 GPR40/FFA1部分激动剂,抑制 [3H]AMG 837 与人类 FFA1受体的特异性结合,pIC50为 8.13。AMG 837 calcium hydrate 可增强啮齿动物的胰岛素分泌并降低葡萄糖水平。
T6017 Linsitinib

OSI-906,林西替尼

IGF-1R Tyrosine Kinase/Adaptors
Linsitinib (OSI-906) 是选择性的、有效的、具有口服活性的IGF-1和胰岛素受体(IR)的双重抑制剂,IC50分别为 35 和 75 nM。
T8329 AR 231453

GPR Endocrinology/Hormones; GPCR/G Protein
AR 231453 是一种口服具有活性的、特异性的 GPR119激动剂。它能够刺激细胞增殖,改善胰岛 β 细胞的功能。
T7127 DC260126

Apoptosis; GPR Apoptosis; Endocrinology/Hormones; GPCR/G Protein
DC260126 是一种 GPR40 (FFAR1)拮抗剂,对棕榈酸酯诱导的内质网应激和凋亡有保护作用。它剂量依赖性地抑制亚油酸、油酸、棕榈油酸和月桂酸刺激的 GPR40 介导的 Ca2+升高,IC50分别 6.28、5.96、7.07和4.58 μM。
T2607 MSDC 0160

CAY10415,Mitoglitazone,MSDC0160,MSDC-0160

Others; IGF-1R; Mitochondrial Metabolism Metabolism; Others; Tyrosine Kinase/Adaptors
MSDC 0160 (CAY10415) 是一种线粒体丙酮酸载体(MPC) 的调节剂,也是调节噻唑烷二酮的线粒体靶标 (mTOT) 的胰岛素增敏剂。它是一种噻唑烷二酮 (TZD),具有抗糖尿病和神经保护活性作用。它具有用于阿尔茨海默氏病的潜力。
T21623 AS1269574

AS 1269574

GPR; TRP/TRPV Channel Endocrinology/Hormones; GPCR/G Protein; Membrane transporter/Ion channel
AS1269574 是口服有效的GPR119激动剂,在表达人 GPR119 的 HEK293 细胞中EC50为 2.5 μM。它激活 TRPA1 阳离子通道,刺激胰高血糖素样肽-1分泌。它仅在高糖条件下特异性诱导胰腺 β 细胞分泌葡萄糖依赖性胰岛素。它在 2 型糖尿病的研究中具有价值。
T7656 Apelin-13

Apelin-13 是存在于中枢和外周神经系统由13个氨基酸组成的多肽序列,是 G 蛋白偶联受体angiotensin II protein J (APJ) 的内源性配体,对 APJ 的 EC50 值为 0.37 nM。Apelin-13 具有扩张血管和降压活性,可用于研究 2 型糖尿病综合征。
T1791 Ceritinib

色瑞替尼,LDK378

Serine Protease; IGF-1R; ALK Angiogenesis; Proteases/Proteasome; Tyrosine Kinase/Adaptors
Ceritinib (LDK378) 是一种选择性,具有口服活性的、ATP 竞争性的 ALK 酪氨酸激酶抑制剂,IC50=200 pM。 它还抑制 IGF-1R (IC50:8 nM),InsR (IC50:7 nM) 和 STK22D (IC50:23 nM)。它显示出良好抗肿瘤效力。
T6419 BMS-536924

HY-10262,胰岛素样生长因子-1 受体拮抗剂,BMS 536924,CS-0117

Apoptosis; FAK; MEK; IGF-1R; Src Angiogenesis; Apoptosis; Cytoskeletal Signaling; MAPK; Tyrosine Kinase/Adaptors
BMS-536924 (BMS 536924) 是一种具有口服活性,竞争性和选择性的胰岛素样生长因子受体激酶和胰岛素受体抑制剂,IC50分别为 100 nM 和 73 nM。它具有抗癌活性。
T22967 MEDICA16

MEDICA 16

GPR; Others; ATP Citrate Lyase Endocrinology/Hormones; GPCR/G Protein; Metabolism; Others
MEDICA16 是 GPR40 的特异性激动剂以及 GPR120 的部分激动剂。 MEDICA16 是一种 ATP-柠檬酸裂解酶抑制剂,可显着降低腓肠肌中的细胞内 TG 含量,同时增加胰岛素敏感性。
T3171 GSK137647A

GSK 137647

GPR Endocrinology/Hormones; GPCR/G Protein
GSK137647A (GSK 137647) 是一种选择性FFA4激动剂,作用于人类和大小鼠FFA4的pEC50分别为6.3、6.1和6.2。
T6080 NVP-AEW541

AEW541

FLT; Tyrosine Kinases; IGF-1R; Autophagy Angiogenesis; Autophagy; Tyrosine Kinase/Adaptors
NVP-AEW541 (AEW541) 是一种IGF-1R 抑制剂,IC50为 0.15 μM。它也抑制InsR,IC50为 0.14 μM。
T1781 GW9508

GW 9508

GPR; Potassium Channel Endocrinology/Hormones; GPCR/G Protein; Membrane transporter/Ion channel
GW 9508 是一种选择性 G 蛋白偶联受体FFA1(GPR40) 和GPR120激动剂。它是一种葡萄糖敏感性胰岛素促分泌剂和 ATP 敏感性钾通道开放剂,具有抗炎和抗动脉粥样硬化活性。
T1791L Ceritinib dihydrochloride

LDK378 dihydrochloride,双盐酸盐色瑞替尼

IGF-1R; ALK Angiogenesis; Tyrosine Kinase/Adaptors
Ceritinib dihydrochloride (LDK378 dihydrochloride) 是一种选择性的、口服具有活性的、ATP 竞争性的ALK 酪氨酸激酶抑制剂 (IC50:200 pM)。它还抑制IGF-1R (IC50:8 nM),InsR (IC50:7 nM) 和 STK22D (IC50:23 nM)。它显示出良好的抗肿瘤作用。
T1918 NVP-TAE 226

TAE226

Apoptosis; FAK; c-Met/HGFR; PYK2; IGF-1R Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
NVP-TAE 226 (TAE226) 是一种具有 ATP 竞争性的双重FAK 和IGF-1R 抑制剂,IC50分别为 5.5 nM、140 nM。它还抑制Pyk2、胰岛素受体,IC50分为 3.5 nM、40 nM。
T6079 NVP-ADW742

ADW742,ADW,GSK 552602A

Apoptosis; IGF-1R Apoptosis; Tyrosine Kinase/Adaptors
NVP-ADW742 (ADW) 是一种具有口服活性,选择性的IGF-1R 酪氨酸激酶抑制剂,IC50为 0.17 μM。它抑制胰岛素受体,IC50为 2.8 μM,在肿瘤细胞中诱导多效性抗增殖/促凋亡。
T2693 AG1024

Tyrphostin AG 1024,Tyrphostin,AGS 200

Apoptosis; IGF-1R Apoptosis; Tyrosine Kinase/Adaptors
AG1024 (Tyrphostin) 是一种可逆的,竞争性和选择性的胰岛素样生长因子-1 受体抑制剂,IC50为 7 μM。它抑制胰岛素受体的磷酸化,IC50值为 57 μM。它诱导细胞凋亡并具有抗癌活性。
T26656 ARH-049020

X334,X-334,X 334,ARH 049020

ARH-049020, a peroxisome proliferator-activated receptor (PPAR) agonist, is used potentially for the treatment of insulin resistance and type 2 diabetes.
T27303 Farglitazar

GI-262570,GI-2570,GW 262570X,GI 262570,GI262570

PPAR DNA Damage/DNA Repair; Metabolism
Farglitazar (GI-262570) 是一种 PPAR-γ 激动剂,是胰岛素增敏剂,通过氧化物酶体增殖物激活受体γ,抑制星状细胞活化,可用于研究糖尿病。
T8780 AMG131

INT-131,AMG-131,CHS 131

PPAR DNA Damage/DNA Repair; Metabolism
AMG131 (CHS 131) 是一种新型非噻唑烷二酮(TZD) 选择性过氧化物酶体增殖物激活受体 (PPAR) γ 调节剂,可用于治疗 2 型糖尿病。
T68405 KW-2450 free base

IGF-1R Tyrosine Kinase/Adaptors
KW-2450 free base 是一种 IGF-1R/IR和酪氨酸激酶多重抑制剂 具有抗肿瘤活性。KW-2450 free base 在小鼠 HT-29/GFP 结肠癌异种移植模型中显示出适度的生长抑制活性并抑制 IGF-1 诱导的信号转导。
T37588L GIP (1-30) amide, porcine acetate

IGF-1R Tyrosine Kinase/Adaptors
GIP (1-30) amide, porcine acetate 是完全葡萄糖依赖性促胰岛素多肽 (GIP) 受体的激动剂。它可弱抑制胃酸分泌,强烈刺激胰岛素。
T15810 LY2922470

GPR Endocrinology/Hormones; GPCR/G Protein
LY2922470 是选择性口服有效的GPR40激动剂,作用于 人 GPR40、小鼠 GPR40、大鼠 GPR40 的EC50值分别为 7 nM、1 nM、3 nM。它可降低血糖水平,同时显著增加胰岛素和 GLP-1,有潜力用于 2 型糖尿病的研究。
T17177 TUG-424

TUG424

Others Others
TUG-424 是一种有效且选择性的游离脂肪酸受体 1 (FFA1/GPR40) 激动剂,EC50 为 32 nM。TUG-424 在 100 nM 处显著增加葡萄糖刺激的胰岛素分泌。TUG-424 可能有助于探索 FFA1 在糖尿病或肥胖等代谢性疾病中的作用。
T6745 5-Iodotubercidin

5-碘代杀结核菌素,5-ITu,NSC 113939

Adenosine Receptor GPCR/G Protein; Neuroscience
5-Iodotubercidin (NSC-113939) 是一种 ATP 类似物,有效抑制腺苷激酶,IC50为 26 nM。它可以激活磷酸化酶和糖原合成酶,在离体肝细胞中启动糖原合成。它也抑制 CK1、胰岛素受体酪氨酸激酶、磷酸化酶激酶、PKA、CK2、PKC 和 Haspin 。
T34973 Tyrphostin 8

4-Hydroxybenzylidenemalononitrile

EGFR; GTPase Angiogenesis; GPCR/G Protein; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) 是一种有效的 GTP 酶抑制剂,对 EGFR 激酶有抑制作用, IC50 值为 560 μM。Tyrphostin 8 可抑制蛋白丝氨酸/苏氨酸钙调磷酸酶 (IC50=21 μM),增强 Caco-2 细胞中转铁蛋白受体介导的转吞作用,并增加口服胰岛素 - 转铁蛋白的降血糖作用。
T69146 Suksdorfin

PPAR DNA Damage/DNA Repair; Metabolism
Suksdorfin 具有降血糖作用,可促进脂肪细胞分化并增强脂联素的产生,可激活过氧化物酶体增殖物激活受体 γ (PPARγ),可促进脂肪细胞对胰岛素依赖性葡萄糖的摄取,可用于肥胖相关研究。
T78097L Mazdutide acetate(2259884-03-0 free base)

Mazdutide acetate(2259884-03-0 free base),OXM-3 acetate,LY-3305677 acetate,IBI-362 acetate

Glucagon Receptor GPCR/G Protein
Mazdutide acetate 是一种高效的胰高血糖素样肽 (GLP-1R) 与胰高血糖素受体 (GCGR) 的共激动剂,是一种胃泌酸调节素类似物。Mazdutide acetate可刺激小鼠胰岛的胰岛素分泌 ,可用于研究肥胖和 2 型糖尿病 (T2D) 。
T62105 NT219

NT-219

STAT JAK/STAT signaling; Stem Cells
NT219 是一种胰岛素受体底物 1/2 (IRS1/2) 和STAT3的双重抑制剂,可增强错误折叠的朊病毒蛋白的聚集NT219 影响,可提高某些分子伴侣的水平,抑制 STAT3 磷酸化。NT219 具有研究癌症和神经退行性疾病。
T3550 X-376

Ensartinib,X-396,恩沙替尼

c-Met/HGFR; ALK Angiogenesis; Tyrosine Kinase/Adaptors
X-376 (Ensartinib) 是一种有效的ALK 抑制剂,对许多具有crizotinib 抗性的ALK 突变型和中枢神经系统转移具有高活性。它能有效地抑制野生型ALK 和ALK 变体(F1174, C1156Y, L1196M, S1206R, T1151和G1202R 突变型),IC50小于4 nM。
T76810 Ganitumab

AMG 479

IGF-1R Tyrosine Kinase/Adaptors
Ganitumab (AMG 479) 是一种高效的1型胰岛素样生长因子受体 (IGF1R) 单克隆抗体。Ganitumab 在低浓度下识别与 IGF1R 结合,KD 值为0.22 nM,Ganitumab 对小鼠 IGF1R 与 IGF1 和 IGF2 的相互作用有抑制作用。Ganitumab 可用于研究癌症。
T15368L Galantide acetate

Galantide acetate(138579-66-5 Free base)

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
Galantide acetate 是一种特殊的甘丙肽受体 (galanin receptor) 拮抗剂,是一种由甘丙肽和 P 物质片段组成的肽段,在大鼠下丘脑可识别两类甘丙肽结合位点 (KD 分别小于 0.1 nM 和 ~6 nM)。Galantide 剂量依赖性 (IC50=1.0 nM) 拮抗甘丙肽介导的葡萄糖诱导的小鼠胰岛胰岛素分泌抑制。Galantide acetate 似乎与单一的 SP 受体群结合 (KD~40 nM)。
T22715 Demethylasterriquinone B1

Others Others
insulin receptor (IR) activator
T28983 TLK19781

TLK 19781,TLK-19781

TLK19781 is an insulin receptor modulator.
T14142 AGL-2263

IGF-1R Tyrosine Kinase/Adaptors
AGL-2263 is a blocker of insulin receptor (IR)
T25123 AZ12253801

AZ 12253801,AZ-12253801

AZ12253801 is a type 1 insulin-like growth factor receptor (IGF-1R) inhibitor.
T36584 HNMPA-(AM)3

Tyrosine Kinases Tyrosine Kinase/Adaptors
HNMPA-(AM)3 抑制 ERK 磷酸化的激活以及促促胸腺激素 (PTTH) 刺激蜕皮类固醇产生。 此外,HNMPA-(AM)3 对蜕皮类固醇产生 (IC50=14.2 μM) 和胰岛素受体活性 (IC50=14.2 μM 和 200 μM,在蚊子和哺乳动物中分别) 具有抑制作用。
T69633 TCS-401

TCS-401 is an insulin receptor sensitizing agent; Selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B).

化合物

Insulin (human)
Cat.No: T8221
Synonym: INSULIN,甘精胰岛素,胰岛素,Insulin(human)
Target: IGF-1R
Insulin(cattle)
Cat.No: TP1125
Synonym: 牛胰岛素,Insulin from bovine pancreas,胰岛素
Target: IGF-1R
[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153)
Cat.No: TP1259
Synonym: [pTyr1146][pTyr1150][pTyr1151]Insulin Receptor 1142-1153,Insulin Receptor 1142-1153
Target:
MID-1
Cat.No: T8773
Synonym:
Target: Others, IGF-1R
Phentolamine
Cat.No: T8348
Synonym:
Target: Adrenergic Receptor
SU4984
Cat.No: T9030
Synonym:
Target: FGFR, IGF-1R, PDGFR
GSK1904529A
Cat.No: T6003
Synonym: GSK 4529
Target: Apoptosis, Raf, VEGFR, IGF-1R, Syk
HNMPA
Cat.No: T21761
Synonym:
Target: IGF-1R
BMS-754807
Cat.No: T2349
Synonym:
Target: Trk receptor, c-Met/HGFR, IGF-1R
GSK1838705A
Cat.No: T3079
Synonym:
Target: IGF-1R, JNK, S6 Kinase, ALK
BIBO3304 TFA
Cat.No: T10539
Synonym:
Target: Neuropeptide Y Receptor
GRK5-IN-2
Cat.No: T9609
Synonym:
Target: GRK
AMG 837 calcium hydrate
Cat.No: TQ0020
Synonym:
Target: GPR
Linsitinib
Cat.No: T6017
Synonym: OSI-906,林西替尼
Target: IGF-1R
AR 231453
Cat.No: T8329
Synonym:
Target: GPR
DC260126
Cat.No: T7127
Synonym:
Target: Apoptosis, GPR
MSDC 0160
Cat.No: T2607
Synonym: CAY10415,Mitoglitazone,MSDC0160,MSDC-0160
Target: Others, IGF-1R, Mitochondrial Metabolism
AS1269574
Cat.No: T21623
Synonym: AS 1269574
Target: GPR, TRP/TRPV Channel
Apelin-13
Cat.No: T7656
Synonym:
Target:
Ceritinib
Cat.No: T1791
Synonym: 色瑞替尼,LDK378
Target: Serine Protease, IGF-1R, ALK
BMS-536924
Cat.No: T6419
Synonym: HY-10262,胰岛素样生长因子-1 受体拮抗剂,BMS 536924,CS-0117
Target: Apoptosis, FAK, MEK, IGF-1R, Src
MEDICA16
Cat.No: T22967
Synonym: MEDICA 16
Target: GPR, Others, ATP Citrate Lyase
GSK137647A
Cat.No: T3171
Synonym: GSK 137647
Target: GPR
NVP-AEW541
Cat.No: T6080
Synonym: AEW541
Target: FLT, Tyrosine Kinases, IGF-1R, Autophagy
GW9508
Cat.No: T1781
Synonym: GW 9508
Target: GPR, Potassium Channel
Ceritinib dihydrochloride
Cat.No: T1791L
Synonym: LDK378 dihydrochloride,双盐酸盐色瑞替尼
Target: IGF-1R, ALK
NVP-TAE 226
Cat.No: T1918
Synonym: TAE226
Target: Apoptosis, FAK, c-Met/HGFR, PYK2, IGF-1R
NVP-ADW742
Cat.No: T6079
Synonym: ADW742,ADW,GSK 552602A
Target: Apoptosis, IGF-1R
AG1024
Cat.No: T2693
Synonym: Tyrphostin AG 1024,Tyrphostin,AGS 200
Target: Apoptosis, IGF-1R
ARH-049020
Cat.No: T26656
Synonym: X334,X-334,X 334,ARH 049020
Target:
Farglitazar
Cat.No: T27303
Synonym: GI-262570,GI-2570,GW 262570X,GI 262570,GI262570
Target: PPAR
AMG131
Cat.No: T8780
Synonym: INT-131,AMG-131,CHS 131
Target: PPAR
KW-2450 free base
Cat.No: T68405
Synonym:
Target: IGF-1R
GIP (1-30) amide, porcine acetate
Cat.No: T37588L
Synonym:
Target: IGF-1R
LY2922470
Cat.No: T15810
Synonym:
Target: GPR
TUG-424
Cat.No: T17177
Synonym: TUG424
Target: Others
5-Iodotubercidin
Cat.No: T6745
Synonym: 5-碘代杀结核菌素,5-ITu,NSC 113939
Target: Adenosine Receptor
Tyrphostin 8
Cat.No: T34973
Synonym: 4-Hydroxybenzylidenemalononitrile
Target: EGFR, GTPase
Suksdorfin
Cat.No: T69146
Synonym:
Target: PPAR
Mazdutide acetate(2259884-03-0 free base)
Cat.No: T78097L
Synonym: Mazdutide acetate(2259884-03-0 free base),OXM-3 acetate,LY-3305677 acetate,IBI-362 acetate
Target: Glucagon Receptor
NT219
Cat.No: T62105
Synonym: NT-219
Target: STAT
X-376
Cat.No: T3550
Synonym: Ensartinib,X-396,恩沙替尼
Target: c-Met/HGFR, ALK
Ganitumab
Cat.No: T76810
Synonym: AMG 479
Target: IGF-1R
Galantide acetate
Cat.No: T15368L
Synonym: Galantide acetate(138579-66-5 Free base)
Target: Neuropeptide Y Receptor
Demethylasterriquinone B1
Cat.No: T22715
Synonym:
Target: Others
TLK19781
Cat.No: T28983
Synonym: TLK 19781,TLK-19781
Target:
AGL-2263
Cat.No: T14142
Synonym:
Target: IGF-1R
AZ12253801
Cat.No: T25123
Synonym: AZ 12253801,AZ-12253801
Target:
HNMPA-(AM)3
Cat.No: T36584
Synonym:
Target: Tyrosine Kinases
TCS-401
Cat.No: T69633
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T3386 Kaempferitrin

Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside,山奈苷

cell cycle arrest; Glucokinase; IGF-1R Cell Cycle/Checkpoint; Metabolism; Tyrosine Kinase/Adaptors
Kaempferitrin (Lespenephryl) 是天然黄酮苷类化合物,具有缓解疼痛、抗糖尿病、消炎、抗肿瘤和化疗作用,可激活胰岛素信号传导。
T0760 Cholesterol

Cholesterin,Cholesteryl alcohol,胆固醇

Estrogen Receptor/ERR; MRP; Endogenous Metabolite; ROR Endocrinology/Hormones; Immunology/Inflammation; Metabolism
Cholesterol (Cholesteryl alcohol) 属于天然产物,是哺乳动物中的主要固醇,是一种雌激素相关受体 α (ERRα) 的激动剂。Cholesterol 广泛存在于动物的细胞膜,也是合成几种重要荷尔蒙及胆酸的材料。
T1286 Vincamine

Angiopac,Oxybral,Devincan,Novicet,Equipur,长春胺,Perval

GPR; Others Endocrinology/Hormones; GPCR/G Protein; Others
Vincamine (Perval) 是从长春花中提取的单萜类吲哚生物碱,可作为外周血管扩张剂,对脑微血管循环有选择性的血管调节作用。它可改善体内葡萄糖稳态,对 2 型糖尿病具有研究潜力。它是GPR40激动剂,通过改善 β 细胞功能障碍和促进葡萄糖刺激型胰岛素分泌发挥 β 细胞保护作用。
T2755 Rhoifolin

野漆树苷,Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside

Others; p38 MAPK; NF-κB; transporter; IGF-1R; Autophagy Autophagy; MAPK; Metabolism; NF-κB; Others; Tyrosine Kinase/Adaptors
Rhoifolin (Apigenin 7-O-neohesperidoside) 是从琯溪蜜柚叶子分离的一种黄酮糖苷。它通过 RANKL 诱导的NF-κB 和MAPK 途径改善钛颗粒刺激的骨溶解并减少破骨细胞生成。它通过增强脂联素分泌,胰岛素受体-β的酪氨酸磷酸化和GLUT4易位有助于治疗糖尿病并发症。
T2P2919 (2S,3R,4S)-4-Hydroxyisoleucine

(4S)-4-Hydroxy-L-isoleucine,(4S)4-羟基异亮氨酸,Hydroxyisoleucine

PI3K PI3K/Akt/mTOR signaling
(2S,3R,4S)-4-Hydroxyisoleucine (Hydroxyisoleucine) 是分离自胡芦巴中的一种可口服的有效成分,具有抗糖尿病、抗糖尿病肾病的作用。
T4S0295 Apigenin 7-glucoside

波斯菊,Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,芹甙元-7-葡萄糖苷,Thalictiin,Apigetrin

Reactive Oxygen Species; HIV Protease Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
Apigenin 7-glucoside (Cosmosiin) 是一种 ROS 清除剂,具有抗增殖、抗氧化作用。
T13803 N-Oleoyl glycine

Cannabinoid Receptor; Akt; Endogenous Metabolite; PPAR Cytoskeletal Signaling; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; PI3K/Akt/mTOR signaling
N-Oleoyl glycine 是一种脂氨酸。在 3T3-L1 脂肪细胞中,N-Oleoyl glycine 通过激活CB1受体和Akt 信号通路来刺激脂肪形成。
TWO2727 Propane-1,2,3-triyl tripalmitate

Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate,三棕榈酸甘油酯

Others; Endogenous Metabolite Metabolism; Others
Propane-1,2,3-triyl tripalmitate (Glycerol Tripalmitate) 是内源性代谢产物的一种。
T3S0027 Picropodophyllotoxin

AXL 1717,Picropodophyllin,苦鬼臼毒素

IGF-1R Tyrosine Kinase/Adaptors
Picropodophyllotoxin (AXL 1717) 是一种环木脂素生物碱,存在于五月树(Podophyllum peltatum) 中,是一种具有潜在抗肿瘤活性的胰岛素样生长因子 1 受体 (IGF1R) 的小分子抑制剂。它特异性抑制 IGF1R 的活性并下调细胞表达,而不干扰其他生长因子受体的活性,例如胰岛素受体、表皮生长因子、血小板衍生生长因子、成纤维细胞生长因子和肥大/干细胞生长因子 (KIT) )。该药剂在抑制肿瘤细胞增殖和诱导肿瘤细胞凋亡方面显示出有效的活性。 IGF1R 是一种在多种人类癌症中过度表达的受体酪氨酸激酶,在多种癌细胞的生长和存活中起关键作用。
T2P2923 Stearic acid

硬脂酸,Isostearic acid,Octadecanoic acid,Cetylacetic acid

Phosphatase; Endogenous Metabolite Metabolism
Stearic acid (Cetylacetic acid) 是长链饱和脂肪酸,存在于许多动植物油脂中。
T3S1612 kuwanon G

桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G

Phosphatase; Antibacterial; Bombesin Receptor; AChR; AChE; Glucosidase GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
Kuwanon G (Moracenin B) 是一种从桑树中得到的黄酮类蛙皮素受体拮抗剂,具有杀菌作用。
T68746 Chaetochromin

Chaetochromin also known as 4548-G05 and NSC 345647, is an orally active, small-molecule, selective agonist of the insulin receptor. It has potent and long-lasting antidiabetic activity in vivo in mice.
T83915 Norbixin hydrate

Norbixin是一种在B. orellana中发现的类胡萝卜素,具有多样的生物活性。在无细胞测试中,它与过氧化物酶体增殖物激活受体γ (PPARγ)结合(Ki = 1.15 µM)。在心脑血管代谢综合征大鼠模型中,Norbixin (47.7 mg/kg) 能够减轻高血糖、高胰岛素血症和胰岛素抗性,降低血清脂质水平及心脏中硫代巴比妥酸反应性物质(TBARS)和谷胱甘肽(GSH)的水平。在胆固醇诱导的动脉粥样硬化兔模型中,它降低氧化型LDL和主动脉蛋白氧化水平,并减少动脉粥样硬化面积。Norbixin(每天0.1和1 mg/kg)减少汞诱导的大鼠肝细胞和白细胞DNA损伤。此外,它还能预防与年龄相关的黄斑变性(AMD)Abca4-/- Rdh8-/-小鼠模型中的光感受器退化。

天然产物

Kaempferitrin
Cat.No: T3386
Synonym: Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside,山奈苷
Target: cell cycle arrest, Glucokinase, IGF-1R
Cholesterol
Cat.No: T0760
Synonym: Cholesterin,Cholesteryl alcohol,胆固醇
Target: Estrogen Receptor/ERR, MRP, Endogenous Metabolite, ROR
Vincamine
Cat.No: T1286
Synonym: Angiopac,Oxybral,Devincan,Novicet,Equipur,长春胺,Perval
Target: GPR, Others
Rhoifolin
Cat.No: T2755
Synonym: 野漆树苷,Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside
Target: Others, p38 MAPK, NF-κB, transporter, IGF-1R, Autophagy
(2S,3R,4S)-4-Hydroxyisoleucine
Cat.No: T2P2919
Synonym: (4S)-4-Hydroxy-L-isoleucine,(4S)4-羟基异亮氨酸,Hydroxyisoleucine
Target: PI3K
Apigenin 7-glucoside
Cat.No: T4S0295
Synonym: 波斯菊,Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,芹甙元-7-葡萄糖苷,Thalictiin,Apigetrin
Target: Reactive Oxygen Species, HIV Protease
N-Oleoyl glycine
Cat.No: T13803
Synonym:
Target: Cannabinoid Receptor, Akt, Endogenous Metabolite, PPAR
Propane-1,2,3-triyl tripalmitate
Cat.No: TWO2727
Synonym: Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate,三棕榈酸甘油酯
Target: Others, Endogenous Metabolite
Picropodophyllotoxin
Cat.No: T3S0027
Synonym: AXL 1717,Picropodophyllin,苦鬼臼毒素
Target: IGF-1R
Stearic acid
Cat.No: T2P2923
Synonym: 硬脂酸,Isostearic acid,Octadecanoic acid,Cetylacetic acid
Target: Phosphatase, Endogenous Metabolite
kuwanon G
Cat.No: T3S1612
Synonym: 桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G
Target: Phosphatase, Antibacterial, Bombesin Receptor, AChR, AChE, Glucosidase
Chaetochromin
Cat.No: T68746
Synonym:
Target:
Norbixin hydrate
Cat.No: T83915
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-01146 Insulin Receptor Protein, Human, Recombinant (long isoform, His)

HHF5,CD220,insulin receptor

Human HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
TMPY-01149 Insulin Receptor Protein, Human, Recombinant (short isoform, His)

Insulin Receptor,HHF5,CD220

Human HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (short isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 106 kDa and the accession number is P06213-2.
TMPY-04395 Insulin Receptor Protein, Human, Recombinant (His & GST)

HHF5,insulin receptor,CD220

Human Baculovirus Insect Cells
Insulin Receptor Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 72.3 kDa and the accession number is P06213-1.
TMPY-05283 Insulin Receptor Protein, Human, Recombinant (long isoform, His), Biotinylated

CD220,Insulin Receptor,HHF5

Human HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
TMPY-00834 IGF1R/CD221 Protein, Human, Recombinant (His)

IGF-I R,IGFR,IGFIR,IGF1 Receptor,JTK13,insulin<...

Human HEK293 Cells
IGF1R/CD221 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81 kDa and the accession number is P08069.
TMPY-06905 IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated

CD221,insulin-like growth factor 1 receptor

Human HEK293 Cells
IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 106.14 kDa and the accession number is NP_000866.1.
TMPY-06195 IGF1R/CD221 Protein, Mouse, Recombinant (His)

insulin-like growth factor 1 receptor,CD22...

Mouse HEK293 Cells
IGF1R/CD221 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 105.2 kDa and the accession number is E9QNX9.
TMPY-04360 IGF1R/CD221 Protein, Human, Recombinant (His & GST)

JTK13,insulin-like growth factor 1 receptor

Human Baculovirus Insect Cells
IGF1R/CD221 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 74.6 kDa and the accession number is P08069.
TMPY-00395 Insulin Protein, Human, Recombinant

IDDM1,MODY10,ILPR,IDDM2,IRDN,IDDM,insulin,INS

Human P. pastoris (Yeast)
INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. The binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Diseases associated with ...
TMPY-02575 PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)

CIMT1,PPARγ,GLM1,PPARgamma,PPARG1,PPARG2,NR1C3,peroxisome pr...

Human Baculovirus Insect Cells
Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling events. The peroxisome proliferator-activated receptor gamma (PPARgamma) regulates osteoblast and osteoclast differentiation, and is the molecular target of thiazolidinediones (TZDs), insulin sensitizers that enhance glucose utilization and adipocyte differentiation. Peroxisome proli...
TMPJ-00387 IL-4R alpha Protein, Mouse, Recombinant (hFc)

Soluble IL-4R-alpha,Interleukin-4 receptor subunit ...

Mouse HEK293 Cells
Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions as receptor for both interleukin 4 and interleukin 13 and couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and chemokine and mucus production at sites of allergic ...
TMPK-00863 LTK Potein, Human, Recombinant (His)

LTK,TYK1

Human HEK293 Cells
Leukocyte tyrosine kinase (LTK) is a receptor tyrosine kinase that belongs to the insulin receptor family. LTK is mainly expressed in pre B cells and brain. LTK Potein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 42.31 kDa and the accession number is P29376-1.
TMPK-00793 LTK Potein, Mouse, Recombinant (His)

LTK,TYK1

Mouse HEK293 Cells
Leukocyte tyrosine kinase (LTK) is a receptor tyrosine kinase that belongs to the insulin receptor family. LTK is mainly expressed in pre B cells and brain. LTK Potein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 42.61 kDa and the accession number is P08923-1.
TMPK-01354 IGF2R Protein, Human, Recombinant (His & Avi)

M6P/IGF2R,IGF-II receptor,MPRI,CI-MPR,CD222,MPR 300...

Human HEK293 Cells
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 164.90 kDa and the accession number is P11717.
TMPK-01361 IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated

MPR 300,IGF-II receptor,M6PR,M6P/IGF2R,CD222,MPRI,C...

Human HEK293 Cells
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 164.90 kDa and the accession number is P11717.
TMPK-01353 IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi)

CI-MPR,MPR 300,MPRI,M6P/IGF2R,M6PR,CD222,IGF-II receptor...

Human HEK293 Cells
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.50 kDa and the accession number is P11717.
TMPJ-00577 INSL3 Protein, Human, Recombinant (His)

RLNL,Insulin-like 3,RLF,Leydig insulin-lik...

Human HEK293 Cells
Insulin-like 3 is a protein that in humans is encoded by the INSL3 gene. It is a secreted protein that belongs to the insulin family. It is expressed in prenatal and postnatal Leydig cells and found as well in the corpus luteum, trophoblast, fetal membranes and breast. It may act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent.It is a ligand for LGR8 receptor.
TMPH-02022 RXFP2 Protein, Human, Recombinant (His & Myc)

Human E. coli
Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3). RXFP2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 21.1 kDa and the accession number is Q8WXD0.
TMPK-01355 IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi)

IGF-II receptor,CI-MPR,CD222,M6P/IGF2R,MPRI,M6PR,MP...

Human HEK293 Cells
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 117.40 kDa and the accession number is P11717.
TMPJ-00781 LR3-IGF-1 Protein, Mouse, Recombinant (His)

IGF1,insulin-like growth factor 1,Insulin-...

Mouse E. coli
Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IG...
TMPH-01385 GLP1R Protein, Human, Recombinant (His)

Human HEK293 Cells
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P43220.
TMPH-03301 GLP1R Protein, Rat, Recombinant (E. coli, His)

Rat E. coli
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.1 kDa and the accession number is P32301.
TMPH-02676 GLP1R Protein, Mouse, Recombinant (His & SUMO)

Mouse E. coli
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.4 kDa and the accession number is O35659.
TMPH-01384 GLP1R Protein, Human, Recombinant (E. coli, His)

Human E. coli
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P43220.
TMPH-03116 IL-4R Protein, Pig, Recombinant (His)

Sus scrofa (Pig) E. coli
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. IL-4R Protein, Pig, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted mo...
TMPY-06864 GLP1R Protein, Human, Recombinant (His & Avi)

glucagon-like peptide 1 receptor

Human HEK293 Cells
Glucagon-like peptide (GLP)-1 receptor is encoded by GLP1R. GLP1R plays a critical role in mediating the biological actions of GLP1 in mammals and fish. The neuronal GLP1Rs mediate body weight and anorectic effects of liraglutide, but are not required for glucose-lowering effects. Glucagon-like peptide 1 receptor (GLP1R) signaling has been shown to have antipsychotic properties in animal models and to impact glucose-dependent insulin release, satiety, memory, and learning in man. Glucagon-like p...
TMPH-02104 Sestrin-3/SESN3 Protein, Human, Recombinant (His & Myc)

Human E. coli
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway. May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses. May prevent the accumulation of reactive oxygen species (ROS) through the alkylhydroperoxide reductase activity born by the N-terminal domain of the protein.
TMPH-01462 HNRNPH1 Protein, Human, Recombinant (GST)

Human E. coli
This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG). HNRNPH1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system...
TMPY-02194 SOCS3 Protein, Human, Recombinant (His & Trx)

SOCS-3,SSI-3,ATOD4,Cish3,SSI3,suppressor of cytokine signali...

Human E. coli
Suppressor of cytokine signaling 3, also known as SOCS-3, Cytokine-inducible SH2 protein 3, CIS-3, STAT-induced STAT inhibitor 3, SOCS3 and CIS3, is a protein which is widely expressed with high expression in heart, placenta, skeletal muscle, peripheral blood leukocytes, fetal and adult lung, and fetal liver and kidney. SOCS3 / CIS3 contains one SH2 domain and one SOCS box domain. SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. ...
TMPJ-00190 CD38 Protein, Mouse, Recombinant (hFc)

ADP-ribosyl cyclase 1,cyclic ADP-ribose hydrolase,T10,CD38

Mouse HEK293 Cells
CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Th...
TMPJ-01074 PKCE Protein, Human, Recombinant (His)

PRKCE,PKCE,nPKC-ε,nPKC-Epsilon,Protein Kinase C Epsilon Type...

Human E. coli
Protein Kinase C Epsilon type is a member of the serine- and threonine-specific protein kinase family that can be activated by calcium and the second messenger diacylglycerol. Protein Kinase C Epsilon contains these domains: one AGC-kinase C-terminal domain, one C2 domain, one protein kinase domain and two phorbol-ester/DAG-type zinc fingers. Protein Kinase C Epsilon phosphorylate a variety of protein targets and has been identified to participate in diverse cellular signaling pathways. It has m...
TMPY-02172 Midkine Protein, Human, Recombinant

midkine (neurite growth-promoting factor 2),NEGF2,MK,ARAP

Human Baculovirus Insect Cells
Midkine (MK or MDK) also known as neurite growth-promoting factor 2 (NEGF2) is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin. Midkine is a retinoic acid-responsive, heparin-binding growth factor expressed in various cell types during embryogenesis. It promotes angiogenesis, cell growth, and cell migration. Midkine is also expressed in several carcinomas, suggesting that it may play a role in tumorigenesis, perhaps through its effects on angio...
TMPH-01503 Humanin Protein, Human, Recombinant (hFc)

Human HEK293 Cells
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation....
TMPH-01502 Humanin Protein, Human, Recombinant (GST)

Human E. coli
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation....

重组蛋白

Insulin Receptor Protein, Human, Recombinant (long isoform, His)
Cat.No: TMPY-01146
Species: Human
Expression System: HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (short isoform, His)
Cat.No: TMPY-01149
Species: Human
Expression System: HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04395
Species: Human
Expression System: Baculovirus Insect Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His), Biotinylated
Cat.No: TMPY-05283
Species: Human
Expression System: HEK293 Cells
IGF1R/CD221 Protein, Human, Recombinant (His)
Cat.No: TMPY-00834
Species: Human
Expression System: HEK293 Cells
IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06905
Species: Human
Expression System: HEK293 Cells
IGF1R/CD221 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-06195
Species: Mouse
Expression System: HEK293 Cells
IGF1R/CD221 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04360
Species: Human
Expression System: Baculovirus Insect Cells
Insulin Protein, Human, Recombinant
Cat.No: TMPY-00395
Species: Human
Expression System: P. pastoris (Yeast)
PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-02575
Species: Human
Expression System: Baculovirus Insect Cells
IL-4R alpha Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00387
Species: Mouse
Expression System: HEK293 Cells
LTK Potein, Human, Recombinant (His)
Cat.No: TMPK-00863
Species: Human
Expression System: HEK293 Cells
LTK Potein, Mouse, Recombinant (His)
Cat.No: TMPK-00793
Species: Mouse
Expression System: HEK293 Cells
IGF2R Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-01354
Species: Human
Expression System: HEK293 Cells
IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-01361
Species: Human
Expression System: HEK293 Cells
IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-01353
Species: Human
Expression System: HEK293 Cells
INSL3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00577
Species: Human
Expression System: HEK293 Cells
RXFP2 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02022
Species: Human
Expression System: E. coli
IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-01355
Species: Human
Expression System: HEK293 Cells
LR3-IGF-1 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00781
Species: Mouse
Expression System: E. coli
GLP1R Protein, Human, Recombinant (His)
Cat.No: TMPH-01385
Species: Human
Expression System: HEK293 Cells
GLP1R Protein, Rat, Recombinant (E. coli, His)
Cat.No: TMPH-03301
Species: Rat
Expression System: E. coli
GLP1R Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02676
Species: Mouse
Expression System: E. coli
GLP1R Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01384
Species: Human
Expression System: E. coli
IL-4R Protein, Pig, Recombinant (His)
Cat.No: TMPH-03116
Species: Sus scrofa (Pig)
Expression System: E. coli
GLP1R Protein, Human, Recombinant (His & Avi)
Cat.No: TMPY-06864
Species: Human
Expression System: HEK293 Cells
Sestrin-3/SESN3 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02104
Species: Human
Expression System: E. coli
HNRNPH1 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01462
Species: Human
Expression System: E. coli
SOCS3 Protein, Human, Recombinant (His & Trx)
Cat.No: TMPY-02194
Species: Human
Expression System: E. coli
CD38 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00190
Species: Mouse
Expression System: HEK293 Cells
PKCE Protein, Human, Recombinant (His)
Cat.No: TMPJ-01074
Species: Human
Expression System: E. coli
Midkine Protein, Human, Recombinant
Cat.No: TMPY-02172
Species: Human
Expression System: Baculovirus Insect Cells
Humanin Protein, Human, Recombinant (hFc)
Cat.No: TMPH-01503
Species: Human
Expression System: HEK293 Cells
Humanin Protein, Human, Recombinant (GST)
Cat.No: TMPH-01502
Species: Human
Expression System: E. coli
TargetMol Loading
联系我们
400-820-0310

上海市静安区江场三路238号8楼